Molecular Cell Biology Notes for M.Sc. Biotechnology | All Units
Explore Molecular Cell Biology lecture notes covering cell structure, membrane transport, protein trafficking, cell cycle regulation, autophagy, apoptosis and cancer biology.
Paper-III Molecular Cell Biology
(Course Code: SOLS/MBT/DSC-9)
No. of Credits: 5
UNIT-I (Cr- 1.5)
Chapter 1: Prokaryotic and eukaryotic cell: Cell structure and organization, cell organelles, and cell wall.
Chapter 2: Structure and function of Nucleus
Chapter 3: Structure and functions of Mitochondria
, Golgi body, endoplasmic
reticulum, chloroplast, lysosome, peroxisome, ribosome and plasma membrane.
Cytoskeleton and its components.
UNIT- II (Cr- 1)
Membrane transportation: Membrane proteins, principle of membrane transport, types of
cellular transport, channel proteins and their types, carrier proteins and functions, ion channels
(Ion selective and voltage-gated ion channels) and membrane potential.
UNIT- III (Cr- 1)
Protein Sorting: Anterograde & retrograde mode of protein trafficking, vesicular transport,
secretory and endocytic pathways, protein folding, unfolded protein response, cell signaling and
their types, crosstalk in signaling pathways, and secondary messengers.
UNIT–IV (Cr- 0.5)
Cell growth: Cell division and differentiation, cell cycle and its regulation (Cyclins, CDK, and
checkpoints), necrosis and its implications.
UNIT-V (Cr- 1)
Autophagy: Process and regulation, role in aging and neurodegenerative diseases.
Programmed cell death: Definition, significance, and types (overview).
Proto-oncogenes, and tumor suppressor genes.
Recommended Books:
1. Alberts, B., Heald, R., Johnson, A., Morgan, D., Raff, M., Roberts, K., Walter, P. Molecular Biology
of the Cell. 2022.7th ed. WW Norton & Co.
2. Lodish, H., Berk, A., Kaiser, C.A. Molecular Cell Biology. 2021. 9th ed. W. H. Freeman & Co.
3. Nelson, D.L., Cox, M.M. Lehninger Principles of Biochemistry. 2021. 8th ed.). W. H. Freeman &
Co.
4. Cooper, G.M., Hausman, R.E. The Cell: A Molecular Approach. 2019. 7th ed. Sinauer Associates
Inc.