Uronic acid (Glucuronate) pathway

Uronic acid (Glucuronate) pathway

April 27, 2022

Uronic acid (Glucuronate) pathway

  • An alternative pathway for the oxidation of glucose that do not produce ATP but used to provide activated form of glucuronate.
  • This pathway is used by plants, certain animals and microorganism to produces Ascorbic Acid (blocked in primates including human).
  • In human it occurs in liver
  • UDP-glucuronate which is mainly used for detoxification of foreign chemicals (drugs) by increasing the solubility of drugs and for the synthesis of mucopolysaccharides such as proteoglycans and glucosaminoglycans.

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