Regulatory Strategies II:​ Zymogen activation and Reversible Covalent Modification

Regulatory Strategies II:​ Zymogen activation and Reversible Covalent Modification

March 11, 2022

Regulatory Strategies II: Zymogen activation and Reversible Covalent Modification

The catalytic activity of the proteins is regulated in four principal ways:

  • Allosteric control
  • Multiple forms of enzymes (Isoenzymes)
  • Proteolytic activation (Zymogen activation) (Digestive enzymes and blood clotting factors)
  • Reversible covalent modification (glycogen phosphorylase)

For details on allosteric control and multiple forms of enzyme please click on

Regulatory Strategies I ​ Allosteric Control of enzymes​ Feedback Inhibition; Properties of Allosteric control; Models for Allosteric regulation:​ The Symmetry Model (MWC model); The Sequential Model (KNF model); ​Allosteric regulation of Aspartate Transcarbomylase (ATCase);​ Different forms of enzymes​ (Isozymes/Isoenzymes)​ Lactate dehydrogenase)​

 

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One response to “Regulatory Strategies II:​ Zymogen activation and Reversible Covalent Modification”

  1. […] Regulatory Strategies II:​ Zymogen activation, Digestive Proteases; Fibrinogen and Prothrombin​;… […]

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