Gene Transfer in Bacteria-3​

Transduction (Generalized and Specialized Transduction)

• Transduction was discovered by in 1952 by Lederberg J and Zinder N in Salmonella typhimurium. ​
• Transduction, the third mechanism of gene transfer in bacteria, differs significantly from transformation and conjugation in that it is mediated by bacterial viruses. ​
• Bacterial genes are incorporated into a phage capsid because of errors that occurs during the virus life cycle.​
• The virus then injects these genes into another bacterium, transferring genetic material one bacterium to another bacterium ​

The transfer of bacterial genes from one bacterium to another bacterium by bacteriophages is known as transduction​

​Types of transduction​

• ​Generalized Transduction in which the phage can transfer any segment of the bacterial genome to another bacterium​
• Specialized transduction in which only restricted segment of the bacterial genome are transferred. Transduction is common mechanism for gene exchange and recombination in bacteria. ​

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