Pentose Phosphate Pathway Overview, Oxidative and non-oxidative phases Reactions and Key enzymes Regulation, Functions and Diseases of HMP Pathway
Pentose Phosphate Pathway: Overview, Phases of HMP shunt (Oxidative and non-oxidative phases); Reactions and Key enzymes
Regulation, Functions and Diseases of HMP pathway
- Also known as: Pentose shunt/Hexose monophosphate shunt/Phosphogluconate pathway
- An alternate pathway of glucose-6 phosphate utilization
- Operates mainly in liver and adipocytes
- Enzymes of HMP shunt are located in cytoplasm to synthesize Reducing power (NADPH) and Pentose sugar (Ribose 5-Phosphate.
Glucose 6-Phosphate in Pentose phosphate Pathway
[…] Glucose has four major fates (in animals and vascular plants); Synthesis of complex polysaccharides (extracellular matrix and cell wall cellulose), Stored as fuels (glycogen, starch, glucose), Oxidized to pyruvate via glycolysis to provide ATP and metabolic intermediates, Oxidized to pentose sugars (nucleotide synthesis) and reducing powers for biosynthetic reactions via pentose phosphate pathway […]
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